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Download Advanced biological active polyfunctional compounds and by Nodar Lekishvili, Gennady Zaikov, Bob Howell PDF

By Nodar Lekishvili, Gennady Zaikov, Bob Howell

ISBN-10: 1612090923

ISBN-13: 9781612090924

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Rev. Biophys. , 1978, 7, 497–526. K. Kuroda. Cytoplasmic Streaming in Plants. Int. Rev. , 1990, 21, 267-307. T. Shimmen. J. , 2007, 120, 1, 31-43. T. Yokota. Curr. Op. Cell Biol. 2004, 16, 227-232. K. Hepler. Cell Mutil. Cytoskeleton. 2007, 64, 3, 217-232. Bougourd, J. A. Feijo. Imaging Plant Cells. : Handbook of Biological Confacal Microscopy. Ed. B. Pawley, New York, 2006, p. 769-787. L. Kudasova. Dependence of Biologic Potentials of the Cell of Nitella flexis on their Age. Coll. Characea Seaweeds and their Application in the Investigation of biologic processes of the cell.

We used a few criterions for the rating of specificity of caffeine center activation. The first: the substance must decrease the Ca2+-accumulating effectiveness. The rate of Ca2+-ATPase function must be not changed at the beginning of reaction, but must activated at the middle and last phases, because all amount of Ca2+accumulated just was released from FSR through the activated RyR. And Ca2+ cannot inhibit Ca2+-ATPase activity from FSR lumen. Second: Ca2+-accumulating effectiveness must be decreased only for caffeine-sensitive FSR, because caffeine-insensitive FSR haven’t any RyR.

Based on quantum-chemical calculations and experimental data, the direction of the reaction of nitration has been established. To model physical properties of biologically active 16 anilides and nitroanilides, we studied quantitative “structure-properties” relationships (QSPR) on the basis of the experimental data. We used several sets of molecular descriptors. The dataset outliers were identified by using Principal Component Analysis (PCA). As a modeling technique, we applied Projections to Latent Structures (PLS).

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